The summit will bring together scientists in the Thyroid and metabolism community and officials of the NIDDK with the goal of fostering research in the areas related to thyroid hormone and its effects on metabolic control. The format will include presentations and discussions by scientists working in this area. Presentations will focus on emerging and relevant areas of thyroid and metabolic pathophysiology that will directly benefit from NIDDK funding.
GOAL: To provide information and updates on the current state-of-the-art of research in thyroid hormones and metabolic control.
| 12:00 → 12:05 |
Welcome |
Antonio Bianco |
| 12:05 → 12:30 |
Thyroid Hormones: The Original Link Between Transcription and Metabolism |
Mitch Lazar |
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| REGULATION AND DYSREGULATION OF THYROID HORMONE SIGNALING |
| CHAIR: RON MARGOLIS AND P. REED LARSEN |
| 12:30 → 12:45 |
Thyroid Hormone Signaling |
Douglas Forrest |
| 12:45 → 13:00 |
Central regulation of the thyroid axis: regulation of energy balance |
Tony Hollenberg |
| 13:00 → 13:15 |
Insulin resistance and thyroid hormone signaling |
Mary-Elisabeth Patti |
| 13:15 → 13:25 |
Discussion |
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| DEIODINATION AND METABOLIC RATE IN HEALTH AND DISEASE |
| CHAIR: IRWIN KLEIN |
| 13:30 → 13:45 |
Dio2, energy expenditure, oxidative stress and insulin resistance |
Antonio Bianco |
| 13:45 → 14:00 |
Dio3, hypoxia, injury and illness |
Stephen Huang |
| 14:00 → 14:15 |
In vivo studies on the activation of thyroid hormones |
Francesco Celi |
| 14:15 → 14:25 |
Discussion |
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- 20 min break - |
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| THYROID HORMONE RECEPTOR ISOFORMS AND METABOLIC CONTROL |
| CHAIR: JACK ROBBINS AND YUN-BO SHI |
| 14:45 → 15:00 |
Thyroid hormone modulation of metabolic pathways |
Gregory Brent |
| 15:00 → 15:15 |
TR isoforms in the control of lipid and carbohydrate metabolism |
Jacques Samarut |
| 15:15 → 15:30 |
Control of adipogenesis by TR isoforms |
Sheue-yann Cheng |
| 15:30 → 15:45 |
The TR alpha 1 aporeceptor and control of metabolism |
Bjorn Vennstrom |
| 15:45 → 16:00 |
Discussion |
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| METABOLIC CONTROL AND THYROID HORMONE ANALOGUES/METABOLITES |
| CHAIR: MARVIN GERSHENGORN |
| 16:05 → 16:20 |
Thyroid hormone analogues and thyronamines |
Thomas Scanlan |
| 16:20 → 16:35 |
Uses of thyroid hormone analogues |
Paul Webb |
| 16:35 → 16:45 |
Discussion |
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