The following represent thyroid-related publications from all ATA-supported grant recipients, arranged by the year the award was made, covering the five year period following the award.
1997
Lynn Burmeister, MD-University of Pittsburgh
“Thyroid hormone dependent modulation of brain function: A PET
Study”
1. Burmeister LA, Pachucki J, St Germain DL 1997. Thyroid hormones inhibit type 2 iodothyronine deiodinase in the rat cerebral cortex by both pre- and posttranslational mechanisms. Endocrinology
2. Zou L, Burmeister LA, Styren SD, Kochanek PM, DeKosky ST 1998. Up-regulation of type 2 iodothyronine deiodinase mRNA in reactive astrocytes following traumatic brain injury in the rat. J Neurochem 71:887-890.
3. Lee E, Chen P, Rao H, Lee J, Burmeister LA 1999. Effect of acute high dose dobutamine administration on serum thyrotrophin (TSH). Clin Endocrinol (Oxf) 50:487-492.
4. Burmeister LA, Ganguli M, Dodge HH, Toczek T, DeKosky ST, Nebes RD 2001. Hypothyroidism and cognition: preliminary evidence for a specific defect in memory. Thyroid 11:1177-1185.
Noriyuki Koibuchi, MD-Brigham and Women's Hospital/Harvard
Medical School
“Thyroid hormone receptor and RORalpha action on neurotrophin
gene expression in the developing cerebellum”
1. Koibuchi N, Fukuda H, Chin WW 1999. Promoter-specific regulation of the brain-derived neurotropic factor gene by thyroid hormone in the developing rat cerebellum. Endocrinology 140:3955-3961.
2. Koibuchi N, Liu Y, Fukuda H, Takeshita A, Yen PM, Chin WW 1999. ROR alpha augments thyroid hormone receptor-mediated transcriptional activation. Endocrinology 140:1356-1364.
3. Martinez dA, Koibuchi N, Chin WW 2000. Coactivator and corepressor gene expression in rat cerebellum during postnatal development and the effect of altered thyroid status. Endocrinology 141:1693-1698.
4. Vasudevan N, Koibuchi N, Chin WW, Pfaff DW 2001. Differential crosstalk between estrogen receptor (ER)alpha and ERbeta and the thyroid hormone receptor isoforms results in flexible regulation of the consensus ERE. Brain Res Mol Brain Res 95:9-17.
5. Kia HK, Krebs CJ, Koibuchi N, Chin WW, Pfaff DW 2001. Co-expression of estrogen and thyroid hormone receptors in individual hypothalamic neurons. J Comp Neurol 437:286-295.
6. Koibuchi N, Yamaoka S, Chin WW 2001. Effect of altered thyroid status on neurotrophin gene expression during postnatal development of the mouse cerebellum. Thyroid 11:205-210.
7. Miyazaki W, Iwasaki T, Takeshita A, Kuroda Y, Koibuchi N 2004. Polychlorinated biphenyls (PCBs) suppress thyroid hormone (TH) receptor (TR)-mediated transcription through a novel mechanism. J Biol Chem (In press)
Stephanie L. Lee, MD, PhD-Boston University
“Novel and multi-disciplinary approach to understanding the physiological
regulation by thyroid hormone of the TRH neurones in the paraventricular
nucleus of the hypothalamus”
1. Fragner P, Lee SL, Aratan dL 2001. Differential regulation of the TRH gene promoter by triiodothyronine and dexamethasone in pancreatic islets. J Endocrinol 170:91-98.
2. Luo LG, Lee SL, Lechan RM, Jackson IM 2001. Effect of preproTRH antisense on thyrotropin-releasing hormone synthesis and viability of cultured rat diencephalic neurons. Endocrine 15:79-85.
Jack Puymirat, MD-CHU Laval Research Center
“Physiopathology of brain dysfunctions in congenital hypothyroidism”
1. Nobrega JN, Raymond R, Puymirat J, Belej T, Joffe RT 1997. Regional changes in beta1 thyroid hormone receptor immunoreactivity in rat brain after thyroidectomy. Brain Res 761:161-164.
2. Baas D, Puymirat J, Sarlieve LL 1998. Posttranscriptional regulation of oligodendroglial thyroid hormone (T3) receptor beta 1 by T3. Int J Dev Neurosci 16:461-467.
3. Martel J, Cayrou C, Puymirat J 2002. Identification of new thyroid hormone-regulated genes in rat brain neuronal cultures. Neuroreport 13:1849-1851.
4. Cayrou C, Denver RJ, Puymirat J 2002. Suppression of the basic transcription element-binding protein in brain neuronal cultures inhibits thyroid hormone-induced neurite branching. Endocrinology 143:2242-2249.
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