American Thyroid Association. Scientists & Physicians Dedicated to Better Understanding & Treatment of Thyroid Diseases.

CLINICAL THYROIDOLOGY January 2009 Volume 21 Issue 1

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Editor: Ernest L. Mazzaferri, MD

Clinical Thyroidology Volume 21, Issue 1, January 2009

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CLINICAL THYROIDOLOGY

Volume 21, Issue 1, January 2009 (PDF File, 1.66 MB, 32 pages)

TABLE OF CONTENTS

CONTENTS

EDITOR’S COMMENTS
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 1.66 MB, 32 pages)

CONCISE REVIEW Novel therapeutic options for aggressive thyroid cancer: Integrating information from the recent clinical trials into clinical practice
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 168 KB, pages 3-7)

EDITOR’S CHOICE — THYROID CANCER Motesanib diphosphate can induce partial remissions in patients with progressive advanced metastatic differentiated thyroid cancer unresponsive to surgery, external beam radiotherapy and 131I
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 203 KB, pages 8-9)

EDITOR’S CHOICE — THYROID CANCER The whole-body radiation delivered by 131I remnant ablation can be significantly reduced by preparing patients with recombinant human thyrotropin rather than with thyroid hormone withdrawal
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 252 KB, pages 10-12)

THYROID NODULES Frozen-section diagnosis of follicular thyroid nodules may have higher specificity and positive predictive value than fine-needle aspiration biopsy, but is not sensitive enough for routine clinical use in most hospitals
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 210 KB, pages 13-15)

GRAVES’ DISEASE IN PREGNANCY Pregnant women with Graves’ disease in remission after antithyroid drug therapy are at high risk of recurrent hyperthyroidism developing during the postpartum period
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 175 KB, pages 16-17)

SUBCLINICAL HYPERTHYROIDISM Subclinical hyperthyroidism is the most prevalent thyroid dysfunction in older Italians and is associated with cognitive impairment
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 184 KB, pages 18-19)

GRAVES’ DISEASE IN CHILDREN The risk of hyperthyroidism relapse following antithyroid drug withdrawal in children with Graves’ disease can be decreased only by a longer initial duration of therapy
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 178 KB, pages 20-21)

THYROIDITIS Serum TSH levels are significantly lower within 30 days after the onset of subacute thyroiditis and remain so for over 60 days, but other routine laboratory tests show little change
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 210 KB, pages 22-23)

THYROID CANCER Acute radiation thyroiditis that sometimes occurs with postthyroidectomy remnant ablation is directly related to thyroidal 131I uptake and not to the amount of 131I used for ablation
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 191 KB, pages 24-26)

THYROID CANCER Extrathyroidal tissue radiation damage from 131I remnant ablation is significantly less with rhTSH preparation than with thyroid hormone withdrawal
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 152 KB, pages 27-28)

THYROID CANCER Rising serum antithyroglobulin antibody levels predict recurrence of differentiated thyroid carcinoma in thyroglobulin-negative patients
Clinical Thyroidology Volume 21 Issue 1 January 2009
(PDF File, 205 KB, pages 29-31)

REVIEWS, DISCLOSURE
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CLINICAL THYROIDOLOGY, published online monthly, is a broad-ranging look at the clinical and preclinical thyroid literature. The Editor searches the world literature for excellent thyroid studies and then summarizes them and provides expert commentary. Please send editorial questions to Dr. Mazzaferri at editorclinthy@thyroid.org.

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