SUMMARY OF THE STUDY
This study was conducted in San Diego County, California. The urinary level of Iodine and perchlorate and the blood level of thyroid hormone, TSH, TPO antibody and Thyroglobulin antibody were measured in 1476 women in early stages of pregnancy.
The statistical analysis showed women with higher level of perchlorate had relatively lower levels of thyroid hormone and higher level of TSH. This effect was modest and not enough to cause major thyroid dysfunction in most women. However, this correlation was more significant in women with a higher level of urinary iodine and in women with positive levels of TPO antibody and Thyroglobulin antibody. The same effect was seen for nitrate and thiocyanate.
WHAT ARE THE IMPLICATIONS OF THIS STUDY?
This study showed that environmental exposure to perchlorate, thiocyanate and nitrate might cause slight changes in thyroid hormone production. The effect would be more concerning in individuals with positive TPO antibody and Thyroglobulin antibody (basically women who are prone to develop thyroid dysfunction). Considering the large number of pregnant women exposed to these substances and the critical role of thyroid hormone in pregnant mother and her unborn baby, attention to this matter is important. Public effort to minimize the contamination of water supply and other forms of environmental exposures to these chemicals is essential.
— Shirin Haddady, MD
ATA THYROID BROCHURE LINKS
Thyroid Disease And Pregnancy: http://www.thyroid.org/thyroid-disease-pregnancy/