Clinical Thyroidology for Patients

Clinical Thyroidology for Patients is a collection of summaries of recently published articles from the medical literature that covers the broad spectrum of thyroid disorders.

Starting with the May 2009 issue, Clinical Thyroidology for Patients will be published on a monthly basis and include summaries of research studies that were discussed in the previous month’s issue of Clinical Thyroidology, a publication of the American Thyroid Association for physicians. Dr. Mazzaferri is the Editor-in-Chief of Clinical Thyroidology.

February 2010 Volume 3 Issue 2

Now available in pdf format for saving and printing and Web page format for viewing online

PDF Format for Saving and Printing
Clinical Thyroidology for Patients February 2010 Volume 3 Issue 2 (PDF file, 629 KB)


Editor’s Comments

THYROID CANCER Motesanib Shows Promise as a New Treatment for Widespread Medullary Thyroid Cancer
Schlumberger et al. Phase II Study of Safety and Efficacy of Motesanib in Patients with Progressive or Symptomatic, Advanced or Metastatic Medullary Thyroid Cancer. J Clin Oncol 2009; 27:3794-3801.
(PDF File for saving and printing, 112 KB)

THYROID AND THE HEART Hypothyroidism Is Not Linked with a Significantly Increased Risk for Coronary Heart Disease
Boekholdt et al. Initial thyroid status and cardiovascular risk factors: The EPIC-Norfolk prospective population study. Clin Endocrinol (Oxf) 2009 doi: 10.1111/j.1365-2265.2009.
(PDF File for saving and printing, 127 KB)

THYROID SURGERY Complications of Thyroid Surgery in Octogenarians Are More Likely Caused by Underlying Illnesses than by Age Alone
Mekel et al. Thyroid surgery in octogenarians is associated with higher complication rates. Surgery 2009;146:913-21.
(PDF File for saving and printing, 91.9 KB)

THYROID CANCER In Patients with Low-Risk Thyroid Cancer, Radioactive Iodine Therapy after Thyroid Hormone Withdrawal or rhTSH Stimulation Is Equally Effective
Elisei et al. Follow-up of low-risk differentiated thyroid cancer patients who underwent radioiodine ablation of postsurgical thyroid remnants after either recombinant human thyrotropin or thyroid hormone withdrawal. J Clin Endocrinol Metab 2009:94(11):4171-9.
(PDF File for saving and printing, 112 KB)

THYROID CANCER Aggressive Surgery in Certain Patients with Familial Medullary Thyroid Cancer Is Safe and Results in High Cure Rates
Schellhaas et al. Prophylactic central neck dissection with total thyroidectomy in familial medullary thyroid cancer with codon 634 mutations is safe and results in high cure rates. Surgery 2009; 146: 906-912.
(PDF File for saving and printing, 118KB)

THYROID CANCER Risk of Metastasis from Papillary Thyroid Cancer Originating in Thyroglossal Duct Cysts
Hartl et al. High rate of multifocality and occult lymph node metastases in papillary thyroid carcinoma arising in thyroglossal duct cysts. Ann Surg Oncol 2009;16:2595-601.
(PDF File for saving and printing, 94.5KB)

HYPERTHYROIDISM Impact of Lithium on Efficacy of Radioactive Iodine Therapy for Graves’ Disease
Bogazzi et al. Impact of Lithium on Efficacy of Radioactive Iodine Therapy for Graves’ Disease: A Cohort Study on Cure Rate, Time to Cure, and Frequency of Increased Serum Thyroxine After Antithyroid Drug Withdrawal. J Clin Endocrinology and Metabolism 95: 201-208 Jan, 2010.
(PDF File for saving and printing, 117 KB)

PEDIATRIC GRAVES’ DISEASE Factors Affecting Response to Radioactive Iodine Therapy in Children with Graves’ Disease
McCormack et al. Radioactive iodine for hyperthyroidism in children and adolescents: referral rate and response to treatment. Clin Endocrinol (Oxf) 2009.
(PDF File for saving and printing, 118 KB)

THYROID NODULES A New Classification System for Thyroid Fine Needle Aspiration Biopsy Results
Theoharis et al. The Bethesda Thyroid fine-needle aspiration classification system: year 1 at an academic institution. Thyroid. 2009 19(11): 1215-23.
(PDF File for saving and printing, 116 KB)

THYROID CANCER Elderly Patients With Thyroid Cancer Have Higher Mortality Rates If Not Treated With Surgery And Radioactive Iodine
Park et al. Treatment patterns of aging Americans with differentiated thyroid cancer. Cancer 2009.
(PDF File for saving and printing, 121 KB)

HIGHLIGHT: Graves’ Disease Foundation Annual Patient and Family Conference