Clinical Thyroidology for Patients

Clinical Thyroidology for Patients is a collection of summaries of recently published articles from the medical literature that covers the broad spectrum of thyroid disorders.

Starting with the May 2009 issue, Clinical Thyroidology for Patients will be published on a monthly basis and include summaries of research studies that were discussed in the previous month’s issue of Clinical Thyroidology, a publication of the American Thyroid Association for physicians. Dr. Mazzaferri is the Editor-in-Chief of Clinical

May 2010 Volume 3 Issue 5

Now available in pdf format for saving and printing and Web page format for viewing online

PDF Format for Saving and Printing
Clinical Thyroidology for Patients May 2010 Volume 3 Issue 5 (PDF file, 890 KB)


Editor’s Comments

THYROID CANCER Patients with spread of papillary thyroid cancer to the lymph nodes at the time of their diagnosis are more likely to experience return of their cancer to lymph nodes over time
Baek et al. Clinical risk factors associated with cervical lymph node recurrence in papillary thyroid carcinoma. Thyroid 2010;20:147-52.
(PDF File for saving and printing, 117 KB)

SUBCLINICAL HYPOTHYROIDISM Reanalysis of the Whickham Survey shows an association of subclinical hypothyroidism and heart disease
Razvi et al. The incidence of ischemic heart disease and mortality in people with subclinical hypothyroidism: Reanalysis of the Whickham survey cohort. J. Clin. Endocrinol. Metab. 2010; 95:00-00 [Epub February 11, 2010].
(PDF File for saving and printing, 140 KB)

GOITER Recombinant Human Thyrotropin (rhTSH) use in the treatment of nontoxic multinodular goiter
Fast et al. Dose-dependent acute effects of recombinant human TSH (rhTSH) on thyroid size and function: comparison of 0.1, 0.3 and 0.9 mg of rhTSH. Clin Endocrinol (Oxf) 2010;72:411-6.
(PDF File for saving and printing, 124 KB)

THYROID CANCER PET scans are very effective at finding spread of thyroid cancer to the lymph nodes in the neck
Kaneko et al. Detection of residual lymph node metastases in high-risk papillary thyroid cancer patients receiving adjuvant I-131 therapy: the usefulness of F-18 FDG PET/CT. Clin Nucl Med 2010;35:6-11.
(PDF File for saving and printing, 120 KB)

THYROID CANCER The first administration of radioiodine following total thyroidectomy for thyroid cancer can destroy metastatic thyroid cancer
Tuttle RM. et al. Radioactive iodine administered for thyroid remnant ablation following recombinant human thyroid stimulating hormone preparation also has an important adjuvant therapy function. Thyroid 2010;20:257-63.
(PDF File for saving and printing, 131 KB)

THYROID AND THE HEART Subclinical Thyroid Dysfunction: Relationship to death from all causes and from cardiovascular disease
Sgarbi et al. Subclinical thyroid dysfunctions are independent risk factors for mortality in a 7.5 year followup: The Japanese-Brazilian thyroid study. European Journal of Endocrinology, 2010. Vol. 162, Issue 3, pp 569-577.
(PDF File for saving and printing, 130 KB)

THYROID CANCER Salivary stimulation with vitamin C at any time after I-131 therapy has no major effect on salivary uptake of I-131
Liu et al. Influence of vitamin C on salivary absorbed dose of 131I in thyroid cancer patients: a prospective, randomized, single-blind, controlled trial. J Nucl Med 2010;4:618-23.
(PDF File for saving and printing, 125 KB)

THYROID AND PREGNANCY Effects of detection and treatment of hypo- and hyperthyroidism in pregnancy
Negro et al. Universal screening versus case finding for detection and treatment of thyroid hormonal dysfunction during pregnancy. J Clin Endocrinol Metab 2010. doi:10.1210/jc.2009-2009
(PDF File for saving and printing, 145 KB)

THYROID CANCER Cancer-associated gene mutation detection in fine needle aspiration biopsies increases the accuracy for diagnosing cancer
Cantara s, et al. Impact of proto-oncogene mutation detection in cytological specimens from thyroid nodules improves the diagnostic accuracy of cytology. J Clin Endocrinol Metab 2010;95:1365-9.
(PDF File for saving and printing, 131 KB)

THYROID CANCER Preparation of thyroid remnant ablation using recombinant human TSH and 30 mCi of I-131 is as effective as thyroid hormone withdrawal
Lee et al. Quality of life and effectiveness comparisons of thyroxine withdrawal, triiodothyronine withdrawal, and recombinant thyroid-stimulating hormone administration for low-dose radioiodine remnant ablation of differentiated thyroid carcinoma. Thyroid 2010;20:173-9.
(PDF File for saving and printing, 139 KB)



What’s New in Thyroid Cancer? A Day for Patients and Their Families
June 12, 2010
Rockefeller Research Laboratories Building
430 East 67th Street (between First & York Avenue)
New York, NY

Multiple Endocrine Neoplasias Patient Education Conference
Saturday, June 26, 2010, 8:30 a.m. – 3:15 p.m.
The University of Texas M. D. Anderson Cancer Center
Houston, TX