The majority of patients in this study were women of all age ranges. The most common reason for taking thyroid hormone was primary hypothyroidism, which includes Hashimoto’s hypothyroidism. Overall, there were no associations found between blood TSH levels (all within the normal range) and measures of general health, well-being, mood, and cognitive function. The authors conclude that taking higher amounts of thyroid hormone within the normal range (resulting in lower blood TSH values within the normal range) does not alter these outcomes.
WHAT ARE THE IMPLICATIONS OF THIS STUDY?
This study shows that higher doses of thyroid hormone to treat hypothyroidism (corresponding to a lower TSH but still within the normal range) do not necessarily have increased health benefits. Specifically, the participants in this study did not have any differences in general health, general well-being, mood, or brain function. The relationships between thyroid status and hypothyroid symptoms are complex. Further research in this field will be helpful to understand why some patients with hypothyroidism who are treated with thyroid hormone replacement continue to have symptoms.
— Angela M. Leung, MD, MSc
ATA THYROID BROCHURE LINKS
Thyroid Hormone Treatment: http://www.thyroid.org/thyroid-hormone-treatment/
Thyroid Function Tests: http://www.thyroid.org/thyroid-function-tests/