Autoimmune diseases occur when the immune system, which usually attacks germs and bacteria, gets confused and attacks our own bodies. Type 1 diabetes mellitus is an autoimmune disease where the insulin-producing cells in the pancreas are destroyed. Hashimoto’s thyroiditis is an autoimmune disease where the thyroid cells are destroyed while Graves’ disease is an autoimmune disease where the immune system turns on the thyroid cells. Patients with type 1 diabetes mellitus have a greater risk to develop autoimmune thyroid disease, especially Hashimoto’s thyroiditis. However, the association between type 2 diabetes mellitus, which is not an autoimmune disease, and autoimmune thyroid disease is less clear. The goal of the study was to investigate the association between type 1 and 2 diabetes mellitus with hypothyroidism and hyperthyroidism.
THE FULL ARTICLE TITLE:
Fleiner HF et al. Prevalence of thyroid dysfunction in autoimmune and type 2 diabetes: the population-based HUNT Study in Norway. J Clin Endocrinol Metab. November 19, 2015 [Epub ahead of print].
SUMMARY OF THE STUDY
The adult population of Nord-Trøndelag in Norway gets surveyed frequently trough the HUNT study. Surveys adults between 1995 and 1997 (HUNT2) and adults between 2006 and 2008 (HUNT3) were included. Participants reported whether they had diabetes mellitus, hypothyroidism or hyperthyroidism and provided a non-fasting blood sample. They also included data from the Norwegian Prescription Database, linking prescription refills with participants after 2004. Antibodies for autoimmune diabetes mellitus or autoimmune thyroid disease were obtained, as well as TSH measurement to evaluate thyroid function. For the analysis, patients older than 40 years were included. Both, the HUNT2 and