All Posts By

ATA

Thyroid®. 2026;0(0)

Thyroid®: Thyroid Hormone Synthesis Without Thyroglobulin

By | Featured, Thyroid Journal

Background: Heterozygosity of genetically encoded misfolded mutant thyroglobulin (TG, the thyroid hormone protein precursor) occurs with a frequency estimated at 1-in-217 people worldwide, resulting in subclinical hypothyroidism that largely escapes medical detection. However, patients carrying biallelic TG mutation, when untreated, are frankly hypothyroid unless and until they develop a massive goiter. To date, TG is the only proven endogenous precursor protein for thyroid hormone synthesis in vertebrates.

Read More
Clinical Thyroidology for the Public

2025 ATA Differentiated Thyroid Cancer Guidelines: Completion Thyroidectomy- Clinical Thyroidology® for the Public

By | Clinical Thyroidology for the Public, Featured, Friends of the ATA

A significant change in the 2025 thyroid cancer guidelines is an increase in the recommendation of lobectomy. Prior guidelines indicate that completion thyroidectomy is considered in up to 20% of patients with a lobectomy and cancer >2 and ≤4 cm. This paper summarizes the changes in recommendations for completion thyroidectomy in the 2025 ATA differentiated thyroid cancer guidelines.

Read More
Clinical Thyroidology for the Public

Development of a model to predict who will need to take a thyroid hormone pill after partial removal of the thyroid gland – Clinical Thyroidology® for the Public

By | Clinical Thyroidology for the Public, Featured, Friends of the ATA, Thyroid Surgery

The study authors reviewed the medical records for all patients who underwent partial thyroidectomy at their institution between 2013 and 2020. They identified 425 patients who met study criteria. The authors then identified which of these patients were prescribed levothyroxine after surgery.

Read More
Lab Education

Laboratory Services for Managing Thyroid Disease: Different and Common Viewpoints of American Thyroid Association Members and of Members of the Endocrine Division of the American Association for Clinical Chemistry

By | Thyroid Lab Spotlight

Professional medical societies frequently use surveys to improve their decision making. When a survey impacts more than one society, cooperation between societies might facil- itate identification of common or disparate priorities, needs, and perceptions, as well as implementation of identified action items.

Read More
Lab Education

Thyroid Stimulating Hormone and Thyroid Hormones (Triiodothyronine and Thyroxine): An American Thyroid Association-Commissioned Review of Current Clinical and Laboratory Status

By | Thyroid Lab Spotlight

This document aims to provide a state-of-the-art status report on the progress achieved in thyroid testing, including thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3). The target audience for this document includes general practitioners, endocrinologists, and laboratory professionals.

Read More
Lab Education

Evaluation of the Current State of Thyroid Hormone Testing in Human Serum—Results of the Free Thyroxine and Thyrotropin Interlaboratory Comparison

By | Thyroid Lab Spotlight

Thyrotropin (TSH) and free thyroxine (fT4) are the two hormones initially measured in blood to assess hypoand hyperthyroidism and to guide treatment decisions.1–3 Some guidelines and recommendations suggest specific concentrations for these hormones to guide decision making.4 Therefore, accurate and reliable TSH and fT4 tests are needed to ensure correct patient care, making the standardization of thyroid function tests to assess both thyroid gland function and therapeutic drug monitoring a priority.

Read More